LONGEVITY NEXUS
Longevity research has shifted from extending lifespan to escaping death entirely. Aubrey de Grey's Longevity Escape Velocity proposes that we'll soon extend life faster than time passes, creating effective immortality. Rapamycin, an immunosuppressant found on Easter Island, extends lifespan in every species tested. NAD+ precursors like NMN aim to reverse cellular aging at the molecular level. Senolytics clear zombie cells that accumulate with age. And cryonics offers a different path entirely — saving the self as information, stored at -196°C, waiting for a future that can read it back. Each approach treats aging as a solvable engineering problem. Together, they form a roadmap to the first post-human future.
Lethometry is an independent research archive investigating the anomalies, gaps, and patterns that mainstream discourse ignores. This section contains every investigation published on the site, organized by category. Each article examines primary sources, academic research, and declassified materials to build cases that challenge conventional narratives. The simulation hypothesis serves as the unifying framework across categories — the question of whether we live in a constructed reality isn't fringe physics anymore, it's the simplest explanation for why our universe looks engineered at every scale, from the Planck length to the cosmic microwave background. Explore the investigations below, follow internal links to trace connections between pieces, or use the navigation to drill into specific categories.
Cellular Reprogramming in 2026: When the Simulation Started Returning Your Refund
Partial reprogramming reached human trials in 2024-2025. The same Yamanaka factors that earned a 2012 Nobel are now being tested as an anti-aging therapy. The implications for the death-as-design-parameter thesis are direct.
LONGEVITY NEXUSThe Ghost in the MRI: When AI Sees What Doctors Don’t
In 2023, Stanford radiologists published a paper that should have made national news. AI systems are detecting cancers in MRI scans that human doctors miss —” consistently, across institutions. The ghost in the machine is real, and it's saving lives.
LONGEVITY NEXUSLongevity Escape Velocity
Can We Outrun the Simulation?